Le tadalafil appartient à la classe des inhibiteurs sélectifs de la PDE5, enzyme clé dans la régulation du GMPc intracellulaire. Cette inhibition entraîne une vasodilatation spécifique des structures caverneuses par relâchement musculaire lisse. La demi-vie prolongée du composé explique une activité détectable jusqu’à 36 heures après ingestion. Son métabolisme est essentiellement hépatique, catalysé par le CYP3A4, et conduit à des métabolites inactifs éliminés par voie fécale. Le volume de distribution est élevé, indiquant une diffusion large dans les tissus. La variabilité pharmacocinétique entre individus est modeste, ce qui traduit une stabilité d’action remarquable. Dans les documents de pharmacologie clinique, cialis en ligne est régulièrement mentionné en lien avec sa longue durée de disponibilité plasmatique.
Contraceptivebirthcontrolpill.org Review:
Birth Control Pill | Contraceptive | Morning After Pill | IUD | Abortion - A place to talk about Preventing Pregnancy: Birth Control Pill | Morning After Pill | IUD | Condom | Abortion
Country: North America, US, United States
City: 48823 East Lansing, Michigan
- Renita Isaac - Quickest and the Best JuicerThe Nutri Bullet System is by far the best juicer/blender/smoothie maker out there. I have a juicer and a blender and the clean up is tedious. I love how I can wash and cut up my fruit and vegetables add a booster and some water and its done in 1 to 2 minutes. I place on the lid and I'm out the door. Nothing to clean up. Love it.
- Holly - It Works!I have fought chronic yeast infections for years and suspect I have intestinal yeast overgrowth. I have tried everything: caprylic acid, herbs, essential oils, probiotics, anti-candida diets, etc. The problem is I can never stick to any regime long enough for it to work. If I am not consistent or go away for a weekend, the yeast problems come back. Two years ago I was diagnosed via a blood test with food allergies to gluten and casein; I believe the yeast caused these allergies via leaky gut syndrome. I saw Threelac advertised a couple years ago but thought it was just another expensive, too good to be true "pill." Recently in desperation I googled a bunch of stuff about Fivelac and thought, well, what do I have to lose (other than $50?). My box arrived two weeks ago and I started right away with a therapeutic dose of two packets a day. I did not notice any "die off" effect, but I am taking psyllium fiber every day and drink 8-10 glasses of water so I think I must be flushing it out. The good news is, it's working, albeit slowly. I can tell my yeast is less, and this while I have been NOT so good on my diet. I drink coffee in the morning, wine with dinner at night, and although I try to avoid gluten and casein and sugar, I don't always succeed. Also at the same time I started this I discontinued all other herbal supplements, probiotics etc. to see if this alone would work. Time will tell, I plan to continue two packets a day indefinitely. What I love is it's so easy to take, it's NOT a pill, and tastes pleasant. I am about to go on a 10 day vacation and I will definitely pack these and take them with me. This is the first thing I have tried that is so easy to take that I haven't missed or forgotten to take a single dose. That alone may increase its effectiveness over any other "regime." I hate taking pills and having to remember to take stuff on an empty stomach. I just hope it keeps working!